Fildena works by inhibiting the enzyme PDE5, which breaks down cGMP (cyclic guanosine monophosphate). By preventing this breakdown, it helps maintain high levels of cGMP, which relaxes the muscles and dilates the blood vessels in the penis, allowing more blood to flow in during sexual arousal, leading to an erection. Sexual stimulation is still required for Fildena to work. It doesn’t cause an erection on its own; it simply aids in achieving and maintaining an erection once aroused. Take the pill with a glass of water, and you can take it with or without food. However, high-fat meals may slow the medication’s onset.